Beyond Thalidomide - Birth Defects Explained

نویسنده

  • Neil McClure
چکیده

This book will appeal to the student of medical history and would be of interest to those entering general practice to obtain some insight into how their specialty evolved in modern times. The book is well written and scholarly and gives the reader a real sense of the evolutionary processes affecting general practice in the mid twentieth century with the foundation of the College of General Practitioners, the emergence of departments of General Practice in medical schools and the establishment of a programme for doctors in training. Tracing Fry’s career one gets a glimpse of health care pre NHS, the establishment of the NHS and its impact on practice and the mysteries of the GP contract.

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منابع مشابه

"The legacy of thalidomide" - A multidisciplinary meeting held at the University of York, United Kingdom, on September 30, 2016.

BACKGROUND Between 1957 and 1962 thalidomide was used as a nonaddictive, nonbarbiturate sedative that also was successful in relieving the symptoms of morning sickness in early pregnancy. Infamously, thousands of babies were subsequently born with severe birth defects. The drug is used again, today, to successfully treat leprosy, and tragically, there is a new generation of thalidomide damaged ...

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Thalidomide Embryopathy: An Enigmatic Challenge

Thalidomide remains one of the world’s most notorious drugs due to the severe birth defects it induced in children between 1957 and 1962. Yet, to some this drug is a lifesaver, as it now enjoys renaissance in the treatment for a wide range of conditions including leprosy, multiple myeloma, Behcet’s disease, and some cancers. However, thalidomide has also been linked to causing a new generation ...

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Causes of birth defects: lessons from history.

Environmental causes of birth defects have increasingly been recognized since the mid-20th century. The teratogenic effects of maternal infections such as rubella and therapeutic drugs such as thalidomide were first reported by alert clinicians. Among clinicians and researchers who have contributed significantly to our knowledge of these environmental causes, Norman Gregg was a Sydney ophthalmo...

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Recognition of thalidomide defects.

Thalidomide: a brief history Thalidomide (alpha-phthalimido-glutarimide) was developed by the German firm Chemie Grunenthal as an anticonvulsant drug. Early trials showed it to be unsuitable for this purpose but indicated that it had sedative properties. Furthermore, it had one remarkable property: overdoses simply caused prolonged sleep, not death. The drug was first marketed in Germany in 195...

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New cases of thalidomide embryopathy in Brazil.

Thalidomide is the best known human teratogen. Although withdrawn from the market in 1961, thalidomide was remarketed after 1965 in several countries, for the treatment of erythema nodosum leprosum. Thalidomide has a potent immunomodulatory property and has now a number of approved and off-label uses in dermatologic, oncologic, infectious and gastrointestinal conditions. In the U.S., FDA approv...

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عنوان ژورنال:
  • The Ulster Medical Journal

دوره 77  شماره 

صفحات  -

تاریخ انتشار 2008